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Radiotherapy, Radiopharmaceuticals and Nuclear Medicine: Global Markets

September 2021 | 219 pages | ID: R540853860BEN
BCC Research

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Report Scope:

This report examines the current and forecasted market potential of radiopharmaceuticals and therapeutics. It offers a detailed analysis of the technological advancement, competitive environment, market background, drivers and restraints, and market growth trends. The research report also includes market projections to 2026. The scope of this report is broad and covers type, production method, technology and applications of radiopharmaceuticals and therapeutics. By type, the market has been segmented into radiotherapy and radiopharmaceuticals. Revenue forecasts from 2021 to 2026 are provided for each segment and regional market, with estimated values derived from manufacturers’ total revenues.

The report also includes a discussion of the major market players in radiopharmaceuticals and therapeutics. Further, it explains the major drivers and regional dynamics of the global radiopharmaceutical and therapeutics market and current trends within the industry.

By geography, the radiopharmaceutical and therapeutics market has been segmented into Europe, North America, Asia-Pacific (APAC) and the Rest of the World (RoW). The detailed analyses of major countries such as the U.S., Germany, Canada, the U.K., Spain, France, Japan, India and China are covered in regional segments. For market estimates, data is provided for 2020 as the base year, 2021 and forecast through year-end 2026. Projected and forecasted revenue values are in constant U.S. dollars that have not been adjusted for inflation.

Report Includes:
  • 52 data tables and 72 additional tables
  • An overview of the global market for radiotherapy, radiopharmaceuticals, and nuclear medicines
  • Estimation of the market size and analyses of the global market trends, with data from 2019 to 2020, estimates for 2021, with projection of CAGR through 2026
  • Analysis of new opportunities, challenges, and technological changes within the industry and highlights of the market potential by type, method, technology, application and region
  • Assessment of present and future strategies within the radiopharmaceuticals market, including radiopharmaceuticals for both diagnostic and therapeutic purposes
  • Description of positron emission tomography (PET) and single photon emission computed tomography (SPECT) and discussion of their applications
  • Evaluation of market opportunities for external beam radiation therapy, internal radiation therapy and systemic radiotherapy
  • Detailed analysis of the current market trends and forecast, relevant R&D activities, new products launches and product enhancement in the industry and discussion of regulatory elements that are affecting the future marketplace
  • Market share analysis of the key companies of the industry and coverage of events like mergers & acquisitions, joint ventures, collaborations or partnerships, and other key market strategies
  • Company profiles of major players in the market, including Accuray Inc., Bayer Pharma AG, Cardinal Health, General Electric Co., Nordion Inc. and Siemens Healthineers AG
CHAPTER 1 INTRODUCTION

Study Goals and Objectives
Reasons for Doing This Study
What's New in This Report?
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

CHAPTER 2 SUMMARY AND HIGHLIGHTS

Highlights of the Market for Radiopharmaceuticals and Therapeutics

CHAPTER 3 REGULATORY SCENARIO

Regulatory Outlook
United States
Canada
Australia
India
European Union

CHAPTER 4 RADIOPHARMACEUTICALS AND THERAPEUTICS: BACKGROUND

Introduction
Uses of Radiopharmaceuticals
Evolution and Transition of Radiopharmaceuticals
Radiotherapy
Ionizing Radiation
Non-ionizing Radiation
Evolution and Transition of Radiation Therapy
The Discovery Period: 1890s
Kilovoltage Era: 1900-1940
Megavoltage Era: 1946-1996
Computer-Assisted Era: 1996-Present
Market Potential
Investment Analysis
Radiotherapy Subsegments
Radiotherapy Subsegments by Type
Radiopharmaceuticals Subsegments by Type
Production Method Subsegments
Technology Subsegments
Radiopharmaceuticals and Therapeutics, by Application

CHAPTER 5 MARKET DYNAMICS

Trends
Respiratory Gating
Proton Therapy
Carbon Ions
Magnetic Resonance-Driven Linear Accelerator
Drivers
Increasing Aging Population
Increasing Incidence of Life-Threatening Diseases
Increasing Incidence of Cancer
High Incidence of Cancer in Aging Population
Growing Healthcare Spending in Emerging Regions
Advancements in Technology
Growing Focus on Early Diagnosis and Treatment
Increasing Number of Cyclotrons
Increasing Amount of Nuclear Imaging Equipment
High Efficiency of Radiotherapy
Palliative Radiation Therapy
Restraints and Challenges
Limited Global Supply of Medical Isotopes
Reimbursement Policies
Regulatory Issues
Expensive Equipment
Lack of Trained Professionals
Limited Effectiveness against Metastatic Cancer
Side Effects of Radiation Therapy
Opportunities
Developing Countries
Replacement of Old Equipment

CHAPTER 6 IMPACT OF COVID-19 PANDEMIC

Introduction
Impact of COVID-19 on Radiopharmaceuticals and Therapeutics
Impact on Cancer Research
Public Health Impact of COVID-19 Across the Cancer Continuum

CHAPTER 7 MARKET BREAKDOWN BY TYPE

Radiotherapy
External Beam Radiation Therapy
Internal Radiation Therapy
Systemic Radiotherapy
Radiopharmaceuticals
Diagnostics
Therapeutics

CHAPTER 8 MARKET BREAKDOWN BY PRODUCTION METHOD

Particle Accelerators (Cyclotrons)
Particle Accelerator Process
Nuclear Reactors
Radionuclide Generators
Production of Radioisotopes Through Radionuclides

CHAPTER 9 MARKET BREAKDOWN BY TECHNOLOGY

External Radiotherapy by Technology
Particle Therapy/Proton Beam Therapy
Stereotactic Radiosurgery (SRS) and Fractionated Stereotactic Radiation Therapy
Image-Guided Radiation Therapy (IGRT)
Intensity-Modulated Radiation Therapy (IMRT)
Tomotherapy
Three-Dimensional Conformal Radiation Therapy (3D-CRT)
Volumetric Modulated Arc Therapy (VMAT)
Internal Radiotherapy by Technology
Pulsed-Dose-Rate (PDR) Brachytherapy
Low-Dose-Rate Brachytherapy
High-Dose-Rate (HDR) Brachytherapy
Systemic Radiotherapy by Technology
Comparison between Alpha and Beta Emitters

CHAPTER 10 MARKET BREAKDOWN BY APPLICATION

External Beam Radiation Therapy
Treatment Planning for External Beam Radiation
Dosing and Treatment with External Beam Radiation
Electron-Emitting High-Energy Linear Accelerators (LINACs)
Internal Radiation Therapy
Applications of Internal Beam Radiation Therapy
Systemic Radiation Therapy
Applications of Systemic Radiation Therapy

CHAPTER 11 MARKET BREAKDOWN BY REGION

North America
United States
Canada
Europe
United Kingdom
France
Germany
Spain
Rest of Europe
Asia-Pacific
China
India
Japan
Australia
Rest of Asia-Pacific
Rest of the World (RoW)

CHAPTER 12 PATENT ANALYSIS

U.S. Patent Analysis
European Patent Analysis
Japanese Patent Analysis

CHAPTER 13 COMPETITIVE LANDSCAPE

Global Company Share Analysis
Mergers and Acquisitions
Agreements, Collaborations, Product Launches and Partnerships

CHAPTER 14 COMPANY PROFILES

ACCURAY INC.
ADVANCED ACCELERATOR APPLICATIONS SA (NOVARTIS)
ALLIANCE MEDICAL GROUP
BAYER PHARMA AG
BECTON, DICKINSON AND CO. (BD)
BRACCO DIAGNOSTIC INC.
CARDINAL HEALTH
COQUI RADIOPHARMACEUTICALS CORP.
CURIUM
ECKERT & ZIEGLER BEBIG
ELEKTA
FUJIFILM HOLDINGS CORP.
GENERAL ELECTRIC CO.
ISO-TEX DIAGNOSTICS INC.
JUBILANT DRAXIMAGE INC.
LANTHEUS MEDICAL IMAGING INC.
NATIONAL CENTRE FOR NUCLEAR RESEARCH POLATOM
NATIONAL INSTITUTE FOR RADIOELEMENTS (IRE)
NORDION INC.
NTP RADIOISOTOPES SOC LTD.
PHARMALUCENCE INC.
PMB ALCEN
SIEMENS HEALTHCARE
VIVOS INC.

LIST OF TABLES

Summary Table: Global Market for Radiopharmaceuticals and Therapeutics, by Region, Through 2026
Table 1: Milestones in the Discovery of Radioactivity and Nuclear Medicine
Table 2: Cancer Incidence and Mortality Statistics, by Region, 2020
Table 3: Investments in Radiopharmaceuticals and Therapeutics
Table 4: Estimated Number of Cancer Cases and Mortality, by Region, Ages 65+
Table 5: Cardiovascular Disease Risk Factors
Table 6: Estimated Number of New Cancer Cases in the U.S., by Cancer Site, 2021
Table 7: Challenges and Strategies Pursued Across Academic Radiology Research Programs in Response to COVID-19 Pandemic
Table 8: Global Market for Radiotherapy, by Type, Through 2026
Table 9: Estimated Age-Standardized Cancer Incidence Rates and Mortality Rates, All Ages in 2020
Table 10: Global Market for External Beam Radiotherapy, by Type, Through 2026
Table 11: Global Market for Compact Radiotherapy Systems, by Type, Through 2026
Table 12: Global Market for Proton Therapy Systems, by Type, Through 2026
Table 13: Global Market for Internal Radiotherapy/Brachytherapy, by Type, Through 2026
Table 14: Global Market for Systemic Radiotherapy, by Type, Through 2026
Table 15: Global Market for Radiopharmaceuticals, by Type, Through 2026
Table 16: Global Pharmaceutical Spending, by Country, 2019
Table 17: Global Market for Diagnostic Radiopharmaceuticals, by Type, Through 2026
Table 18: Global Market for Therapeutic Radiopharmaceuticals, by Type of Therapeutic, Through 2026
Table 19: Global Market for Radiopharmaceuticals, by Production Method, Through 2026
Table 20: Comparison of External Beam Radiation Therapy (EBRT) and Brachytherapy
Table 21: Global Market for External Radiotherapy, by Technology, Through 2026
Table 22: Comparison of Tomotherapy and Conventional Radiotherapy
Table 23: Advantages and Disadvantages of Brachytherapy
Table 24: Various Types of Brachytherapy Implants
Table 25: Brachytherapy Treatment Duration
Table 26: Brachytherapy Treatment Dose Rate
Table 27: Brachytherapy Treatment Source Loading
Table 28: Comparison of Low-Dose and High-Dose Radiation Therapy
Table 29: Benefits and Drawbacks of High-Dose-Rate (HDR) Brachytherapy
Table 30: Comparison of Alpha and Beta Particles
Table 31: Benefits and Drawbacks of Radiopharmaceuticals
Table 32: Global Market for External Beam Radiotherapy, by Application, Through 2026
Table 33: Global Market for Internal Beam Radiotherapy, by Application, Through 2026
Table 34: Commonly Used Radionuclides (Radiation Sources) Half-Life for Brachytherapy
Table 35: Global Market for Systemic Radiotherapy, by Application, Through 2026
Table 36: Global Market for Radiopharmaceuticals and Therapeutics, by Region, Through 2026
Table 37: North American Market for Radiopharmaceuticals and Therapeutics, by Country, Through 2026
Table 38: North American Market for Radiotherapy, by Type, Through 2026
Table 39: North American Market for External Beam Radiotherapy, by Type, Through 2026
Table 40: North American Market for Compact Radiotherapy Systems, by Type, Through 2026
Table 41: North American Market for Proton Therapy Systems, by Type, Through 2026
Table 42: North American Market for Internal Radiotherapy/Brachytherapy, by Type, Through 2026
Table 43: North American Market for Radiopharmaceuticals, by Type, Through 2026
Table 44: North American Market for External Radiotherapy, by Technology, Through 2026
Table 45: Estimated Number of New Cancer Cases among All Ages, in the U.S., 2020
Table 46: U.S. Aging Population, Projections and Trends, 2000-2050
Table 47: Estimated Number of New Cancer Cases among All Ages, in Canada, 2020
Table 48: European Market for Radiopharmaceuticals and Therapeutics, by Country, Through 2026
Table 49: European Market for Radiotherapy, by Type, Through 2026
Table 50: European Market for External Beam Radiotherapy, by Type, Through 2026
Table 51: European Market for Compact Radiotherapy Systems, by Type, Through 2026
Table 52: European Market for Proton Therapy Systems, by Type, Through 2026
Table 53: European Market for Internal Radiotherapy/Brachytherapy, by Type, Through 2026
Table 54: European Market for Radiopharmaceuticals, by Type, Through 2026
Table 55: European Market for External Radiotherapy, by Technology, Through 2026
Table 56: Estimated Number of New Cancer Cases and Deaths among All Ages in the U.K., 2020
Table 57: Estimated Number of New Cancer Cases and Deaths among All Ages in France, 2020
Table 58: Rising Geriatric Population in Germany, 2000-2030
Table 59: Estimated Number of New Cancer Cases and Deaths among All Ages in Germany, 2020
Table 60: Estimated Number of New Cancer Cases and Deaths among All Ages in Spain, 2020
Table 61: Estimated Number of New Cancer Cases and Deaths among All Ages in Italy, 2020
Table 62: Estimated Number of Elderly People (Aged 60+) with Dementia in Denmark, 2017-2040
Table 63: Estimated Number of New Cancer Cases and Deaths among All Ages in the Rest of Europe, 2020
Table 64: Asia-Pacific Market for Radiopharmaceuticals and Therapeutics, by Country, Through 2026
Table 65: Asia-Pacific Market for Radiotherapy, by Type, Through 2026
Table 66: Asia-Pacific Market for External Beam Radiotherapy, by Type, Through 2026
Table 67: Asia-Pacific Market for Compact Radiotherapy Systems, by Type, Through 2026
Table 68: Asia-Pacific Market for Proton Therapy Systems, by Type, Through 2026
Table 69: Asia-Pacific Market for Internal Radiotherapy/Brachytherapy, by Type, hrough 2026
Table 70: Asia-Pacific Market for Radiopharmaceutical, by Type, Through 2026
Table 71: Asia-Pacific Market for External Radiotherapy, by Technology, Through 2026
Table 72: Estimated Number of New Cancer Cases and Deaths among All Ages in China, 2020
Table 73: Estimated Number of New Cancer Cases and Deaths among All Ages in India, 2020
Table 74: Estimated Number of New Cancer Cases and Deaths among All Ages in Japan, 2020
Table 75: Estimated Number of New Cancer Cases and Deaths among All Ages in Australia, 2020
Table 76: Rest of the World Market for Radiotherapy, by Type, Through 2026
Table 77: Rest of the World Market for External Beam Radiotherapy, by Type, Through 2026
Table 78: Rest of the World Market for Compact Radiotherapy Systems, by Type, Through 2026
Table 79: Rest of the World Market for Proton Therapy Systems, by Type, Through 2026
Table 80: Rest of the World Market for Internal Radiotherapy/Brachytherapy, by Type, Through 2026
Table 81: Rest of the World Market for Radiopharmaceuticals, by Type, Through 2026
Table 82: Rest of the World Market for External Radiotherapy, by Technology, Through 2026
Table 83: Leading Causes of Death in Argentina and Percentage Change, 2007-2017
Table 84: Estimated Number of New Cancer Cases and Deaths among All Ages in Latin America, by Country, 2020
Table 85: U.S. Patents on Radiopharmaceuticals and Therapeutics
Table 86: European Patents on Radiopharmaceuticals and Therapeutics
Table 87: Japanese Patents and Patent Applications on Radiopharmaceuticals and Therapeutics
Table 88: Global Company Ranking in the Market for Radiopharmaceuticals, 2020
Table 89: Global Company Ranking in the Market for Therapeutics, by Company, 2020
Table 90: Accuray: Product Portfolio
Table 91: Accuray: Recent Developments, 2019-2021
Table 92: Advanced Accelerator Applications SA: Product Portfolio
Table 93: Advanced Accelerator Applications SA: Recent Developments, 2018 and 2021
Table 94: Alliance Medical Group: Product Portfolio
Table 95: Alliance Medical Group: Recent Developments, 2021
Table 96: Bayer Pharma AG: Product Portfolio
Table 97: Bayer Pharma AG: Recent Developments, 2020
Table 98: BD: Product Portfolio
Table 99: Bracco Diagnostics Inc.: Product Portfolio
Table 100: Cardinal Health: Product Portfolio
Table 101: Cardinal Health: Recent Developments, 2020 and 2021
Table 102: Coquн RadioPharmaceuticals: Product Portfolio
Table 103: Curium: Product Portfolio
Table 104: Curium: Recent Developments, 2019-2021
Table 105: Eckert & Ziegler BEBIG: Product Portfolio
Table 106: Eckert & Ziegler BEBIG: Recent Developments, 2021
Table 107: Elekta: Product Portfolio
Table 108: Elekta: Recent Developments, 2020 and 2021
Table 109: Fujifilm Toyama Chemical Co., Ltd.: Product Portfolio
Table 110: General Electric Co.: Product Portfolio
Table 111: Iso-Tex Diagnostics Inc.: Product Portfolio
Table 112: Jubilant DraxImage Inc.: Product Portfolio
Table 113: Lantheus Medical Imaging Inc.: Product Portfolio
Table 114: National Centre for Nuclear Research Radioisotope Centre POLATOM: Product Portfolio
Table 115: National Institute for Radioelements: Product Portfolio
Table 116: National Institute for Radioelements: Recent Developments, 2020 and 2021
Table 117: Nordion Inc.: Product Portfolio
Table 118: NTP Radioisotopes SOC Ltd.: Product Portfolio
Table 119: Pharmalucence Inc.: Product Portfolio
Table 120: PMB ALCEN: Product Portfolio
Table 121: Siemens Healthcare: Product Portfolio
Table 122: Vivos Inc.: Product Portfolio
Table 123: Vivos Inc.: Recent Developments, 2020

LIST OF FIGURES

Summary Figure: Global Market for Radiopharmaceuticals and Therapeutics, by Region, 2019-2026
Figure 1: Types of Radiation
Figure 2: New Cases of Most Common Cancer, 2020
Figure 3: Estimated Number of Cancer Cases (3 Years), by Country
Figure 4: Respiratory Gating Procedure
Figure 5: Countries with the Highest Expected Percentage of People Age 60 and Older, 2050
Figure 6: Global Trends in Rising Aged Population, 2014-2022
Figure 7: Top 10 Global Causes of Death, 2016
Figure 8: Global Adult Population with Cardiovascular Conditions, by Region, 2019
Figure 9: Global Disease Burden, 2017
Figure 10: Global Aging (65 Years and Above) Population, 1990-2050
Figure 11: Factors Related to Aging and the Promotion of Cancer
Figure 12: Rising Trends in Healthcare Spending, by Institution, 2015-2040
Figure 13: Number of New Cancer Cases in India, by Cancer Site, 2020
Figure 14: Number of New Cancer Cases in China, by Cancer Site, 2020
Figure 15: Potential Impact of the COVID-19 Pandemic on Future Cancer Outcomes
Figure 16: Number of New Cancer Cases among All Ages, by Cancer Type, 2020
Figure 17: Number of Cancer-Related Deaths among All Ages, by Cancer Type, 2020
Figure 18: Types of Beams Used in Radiation Therapy
Figure 19: Leading Causes of Death Globally, by Disease Indication, 2019
Figure 20: Different Types of Diagnostic Radiopharmaceuticals
Figure 21: Types of Therapeutic Radiopharmaceuticals
Figure 22: Different Production Techniques of Radiopharmaceuticals
Figure 23: Block Diagram of Particle Accelerators
Figure 24: Block Diagram of Particle Therapy/Proton Beam Therapy
Figure 25: Block Diagram of Stereotactic Radiosurgery
Figure 26: Procedure of Image-Guided Radiotherapy (IGRT)
Figure 27: Block Diagram of Three-Dimensional Conformal Radiation Therapy (3D-CRT)
Figure 28: LDR Prostate Brachytherapy Procedure
Figure 29: Number of New Cancer Cases in Canada, by Cancer Site, 2020
Figure 30: Distribution of New Cancer Cases in Canada, by Cancer Site, 2020
Figure 31: Number of New Cancer Cases in France, by Cancer Site, 2020
Figure 32: Distribution of New Cancer Cases in France, by Cancer Site, 2020
Figure 33: Number of New Cancer Cases in Germany, by Cancer Site, 2020
Figure 34: Distribution of New Cancer Cases in Germany, by Cancer Site, 2020
Figure 35: Number of New Cancer Cases in Spain, by Cancer Site, 2020
Figure 36: Distribution of New Cancer Cases in Spain, by Cancer Site, 2020
Figure 37: Number of New Cancer Cases in Italy, by Cancer Site, 2020
Figure 38: Distribution of New Cancer Cases in Italy, by Cancer Site, 2020
Figure 39: Distribution of New Cancer Cases in China, by Cancer Site, 2020
Figure 40: Distribution of New Cancer Cases in India, by Cancer Site, 2020
Figure 41: Number of New Cancer Cases in Japan, by Cancer Site, 2020
Figure 42: Distribution of New Cancer Cases in Japan, by Cancer Site, 2020
Figure 43: Distribution of New Cancer Cases in Australia, by Cancer Site, 2020
Figure 44: Number of New Cancer Cases in Africa, by Cancer Site, 2020
Figure 45: Distribution of New Cancer Cases in Africa, by Cancer Site, 2020
Figure 46: Accuray: Annual Revenue, 2018-2020
Figure 47: Accuray: Revenue Share, by Geography, 2020
Figure 48: Accuray: Revenue Share, by Business Segment, 2020
Figure 49: Bayer AG: Annual Revenue, 2018-2020
Figure 50: Bayer AG: Revenue Share, by Geography, 2020
Figure 51: Cardinal Health: Annual Revenue, 2018-2020
Figure 52: Cardinal Health: Revenue Share, by Geography, 2020
Figure 53: Cardinal Health: Revenue Share, by Segment, 2020
Figure 54: General Electric Co.: Annual Revenue, 2018-2020
Figure 55: General Electric Co.: Revenue Share, by Region/Country, 2020
Figure 56: General Electric Co.: Revenue Share, by Business Segment, 2020
Figure 57: Siemens: Annual Revenue, 2019 and 2020
Figure 58: Siemens: Revenue Share, by Segment, 2020


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