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Global Rising Stars Outlook 2015: Innovative Therapies for Treating Diseases are Being Sought after with Fresh Vigor as New Targets

January 2015 | 72 pages | ID: GC060F89217EN
MP Advisors

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Innovative Therapies for treating diseases are being sought after with fresh vigor as new targets , approaches and biology is discovered. One field which is poised to bring a paradigm change in the way diseases are treated in the next decades is the Stem cell therapy/Regenerative Medicine space. The number of companies and products in the clinic have reached a critical mass warranting a close watch for those interested in keeping pace with the development of new medicines. The Regenerative medicine Universe is large and new companies are being added to it rapidly. As a result we have used some filters to select a few names for a detailed coverage in our Outlook this year.

Key Criteria for Our Selection are:-
  • Uniqueness of the Technology platform and the ability to scale up commercially in case of positive outcome of products in the pipeline
  • Pipeline and clinical data analysis
  • Marketed product and commercial tie up. Robustness of the Management, financial and business model.
CESCA THERAPEUTICS INC.: HEDGING THE RISK WITH STEM CELL BASED DEVICES AND THERAPIES AND GLOBAL PRESENCE

Figure 1: Products In Pipeline
Table 1: Clinical Development- Critical Limb Ischemia (ClI)Data Key Milestones

OCATA THERAPEUTICS INC: OPHTHALMIC FOCUS- MACULAR DEGENERATIVE CONDITIONS- LOOKING WITH A NEW EYE

Figure 1: Market For Age-Related Macular Degeneration (AMD)
Figure 2: Products In The Pipeline

ORGENESIS: FOCUS- DIABETES- TRICKING YOUR LIVER TO MAKE INSULIN!

Technology Platform
  Figure 1: Schematic Representation Of Making Autologous Insulin Producing (AIP) Cell

TIGENIX NV: EXPLOITING THE ADIPOSE TISSUE- MULTIPLE APPLICATIONS OF FAT?

Technology Platform
Marketed Products
  Figure 1: Products In Pipeline
Key Milestones

PLURISTEM THERAPEUTICS INC: REGENERATING AND RECYCLING- ALLOGENIC THERAPIES FROM THE PLACENTA

PluriX 3D Technology Platform
Pipeline
Figure 1: Classification Of Peripheral Arterial Disease Types
Market Opportunity
Key Milestones

MESOBLAST: LEADER IN REGENERATIVE SAPCE IN KOREA- FOCUSING ON INTERNATIONAL MARKETS

Technology Platform
Pipeline- Focus on four major areas
  Figure 1: Drugs In The Pipeline
  Figure 2: CHFf Discease Classification And Target Patients In PhIII Trial
  Figure 3: PhiII Data Of MPC-150 In CHF
  Figure 4: Market Opportunity In Chronic Low Back Pain (CLBP)
Key Milestones

MEDIPOST CO LTD: LEADER IN REGENERATIVE SPACE IN KOREA- FOCUSING ON INTERNATIONAL MARKETS

Marketed and Products in the Pipeline
Key Milestones
  Figure 1: Sales By Business Segment

JCR PHARMACEUTICALS CO. LTD.: FIRST STEM CELL BASED PRODUCT IN JAPAN FOR GRAFT-VERSUS-HOST DISEASE (GVHD).

Technology Platform
Product in the Pipeline
Key Milestones
Facts and Financials
  Table 1: Pipeline Table
  Figure 1: Sales By Business Segments

JAPAN TISSUE ENGINEERING CO. LTD: BUILDING CONFIDENCE IN REGENERATIVE MEDICINE- FUJI FILM VENTURE FROM COLORS TO REGENERATIVE MEDICINE-

Plat form Focus
Products
  Figure 1: Therapy and Product Focus

PART II-INDIAN INNOVATORS- RISING STARS:

Table 1: Select new generation innovation /drug discovery Indian companies
Connexios: Maturing Pipeline and Focus on Diabetes/Metabolic Disorders to Drive Visibility
Technology Platform
Therapy Focus—Diabetes/Metabolic Disorder and Non Alcoholic Steatohepatitis (NASH)
Key Milestones
  Table 1: Differences Between G-Protein Coupled Receptor Agonists
  Table 2: Pipeline Of GPR Agonist For Treatment Of Type 2 Diabetes
  Figure 1: Products In Pipeline- Diabetes
  Figure 2: Products In Pipeline For NASH
  Figure 3: Other Programs

CELLWORKS: IN SILICO TECHNOLOGY PLATFORM POISED TO DELIVER- FOCUS ON PERSONALISED MEDICINE AND CANCER

Figure 1: Simulation Based Personalized Medicine
Figure 2: Cellworks Therapeutic Programs

BUGWORKS: IN SILICO TECHNOLOGY PLATFORM BEING APPLIED TO SERIOUS HOSPITAL INFECTIONS- NEED OF THE HOUR!

Therapy focus- Serious Hospital Infection
Technology Platform
  Figure 1: Drug Development Success For TB
  Figure 2: Going Way Froward

TERGENE: AFFORDABLE AND SECOND GENERATION VACCINES- ADDRESSING THE URGENT NEEDS OF EMERGING MARKETS.

Development Strategy and Status
  Figure 1: Sales Of Currently Available Vaccines For Streptococcus Pneumonia
  Figure 2: WW Demand Forecast Of Vaccines For Streptococcus Pneumonia
  Figure 3: Vaccine Market


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